Kevin, a straight laced financial adviser, is invited to his loser older brother Norm's 40th birthday party. The 'party' turns out to be a small gathering of Norm's eccentric friends at a campsite. When one of the friends chokes on a hot dog the group decides to bury him. Unbeknownst to them, they bury him on cursed native American land, and he soon returns possessed by a demon hell bent on fulfilling an ancient vendetta! Antics ensue as Norm, Kevin, and the others run through the desert, the monster in hot pursuit, encountering a few other strange back-woods types as they go. As things get increasingly bizarre and ridiculous with the monster impossible to stop, the brothers find themselves with their backs against the wall; can they find a way to look past their differences and reconcile in the face of their imminent demise?